Supports lymphatic system. Anti-inflammatory action relieves congestion of lymphatic system and glands (swollen lymph nodes). Eases oedema and water retention. Lessens recurring infections. Improves energy levels and recovery after infections. Useful after tonsillitis, glandular fever, lymphangitis and cystitis. Important adjunct in treatment of ulcers resulting from congestive circulatory stasis. Useful support to relieve psoriasis. 50ml herbal tinctures. Ingredients: Each 3ml contains the equivalent of 50mg Echinacea spp., 100mg Hydrastis canadensis, 50mg Galium aperine, 100mg Phytolacca decandra.
An effective liver and digestive detoxifier. Relieves sluggishness, bloating and atonic constipation. Helps the body in waste clearance of accumulated by-products. Improves digestive, liver and kidney function. Liver FlushTM has a hepato-protective action, preventing damage from harmful chemicals and alcohol and aiding recovery of the liver. Constituents act as free radical scavengers and clear heavy metals. Acts as a blood purifier and improves circulation. It also has anti-fungal and anti-parasitic actions. 400mg, 60 capsules. Ingredients: Each capsule contains: 78mg Cinnamonium zeylenium powder, 78mg Centaurium erythraea powder, 78mg Rhamnus purshiana powder, 78mg Zingiber officinalis powder, 78mg Cynara scolymus.
Supports the function of all major organs in the body: Liver, gall bladder, kidneys, bladder, pancreas, spleen and stomach. It is a digestive stimulant and reduces cholesterol. Stimulates bile flow and prevents kidney stone formation. Eases rheumatic conditions. Detoxifying action. 300mg, 60 capsules.
Supports liver function and metabolism. Milk thistle constituents have a prophylactic and protective effect on the liver. Silymarin is an anti-oxidant that reduces hepato-cellular necrosis and fatty deposits in the liver. Itâs regenerative action regenerates injured liver cells, reducing circulatory changes in the hepatic portal system. The anti-inflammatory action decreases SGOT (Serum glutamic oxaloacetic transaminase, a liver enzyme) in patients with chronic liver disease. Lessens risk of gallstone formation. Reduces the impact of environmental toxins and heavy metals. Used for cholelithiasis, liver cirrhosis, inflammatory conditions such as chronic hepatitis and fatty liver, varicosities and haemorrhoids. 400mg, 60 capsules.
FLORA FORCE® TURMERYNNE® capsules with turmeric, cayenne and black pepper, provide antioxidants for the maintenance of good health, and may reduce inflammation. Preliminary research suggests that turmeric (Curcuma longa) and its active constituent, curcumin, may have antioxidant effects. These help to scavenge free radicals. Curcumin also has an anti-inflammatory action. The major active constituent in Cayenne (Capsicum minimum) is capsaicin. Various studies suggest that Capsicum minimum and capsaicin have antioxidant effects and decrease inflammation. Piperine, the active constituent found in Black Pepper (Piper nigrum) increases the oral absorption and bio-availability of other substances. Avoid taking TURMERYNNE® capsules if you are pregnant or breastfeeding.
PATIENT INFORMATION LEAFLET
Information for the Patient about FLORA FORCE® TURMERYNNE® CapsulesInformation currently undergoing review, please refer to Professional Information below.TURMERYNNE® Capsules Western herbal medicine This medicine has not been evaluated by the Medicines Control Council. This medicine is not intended to diagnose, treat, cure or prevent any disease. SCHEDULING STATUS: Not Scheduled PROPRIETARY NAME (AND DOSAGE FORM): TURMERYNNE® Capsules COMPOSITION: Each TURMERYNNE® capsule contains:
ACTIVE INGREDIENT QUANTITY Curcuma longa rhizome powder 215 mg Capsicum minimum fruit powder 215 mg Piper nigrum fruit powder 20 mg
The major active constituents in Curcuma longa are curcuminoids including curcumin. Preliminary research suggests that turmeric and its constituent curcumin may have anti-oxidant effects. Both turmeric and its constituents have been found to scavenge free radicals and phenolic oxidants and decrease levels of reactive oxygen species.
Curcumin has anti-inflammatory activity, possibly by inhibiting cyclooxygenase-2 (COX-s), prostaglandins, leukotrienes and other cytokines involved in pro-inflammatory signalling pathways.
The major active constituent in Capsicum minimum is capsaicin. Various studies suggest that Capsicum minimum and capsaicin have anti-oxidant effects and decrease inflammation.
The active constituent, piperine, found in Piper nigrum increases the oral absorption and bio-availability of other substances.INDICATIONS:
TURMERYNNE® capsules provide anti-oxidants for the maintenance of good health, and may reduce inflammation.CONTRA-INDICATIONS:
TURMERYNNE® capsules are contra-indicated in patients with:
- A hypersensitivity to any of the ingredients in TURMERYNNE®
- Biliary obstruction (bile duct obstruction and gallstones) (see “WARNINGS AND SPECIAL PRECAUTIONS”).
- Bleeding disorders (see “WARNING AND SPECIAL PRECAUTIONS”).
- Diabetes (see “WARNINGS AND SPECIAL PRECAUTIONS”).
- Hypertension (see “WARNINGS AND SPECIAL PRECAUTIONS”).
- Gastro-oesophageal reflux disease.
- Iron deficiency (see “WARNINGS AND SPECIAL PRECAUTIONS”).
- Surgery (see “WARNINGS AND SPECIAL PRECUATIONS”).
- Pregnancy and lactation (see “PREGNACY AND LACTATION”).
TURMERYNNE® capsules should be used with care in patients with cholelithiasis (gallstones) and should only be used after consultation with a physician (see “CONTRA-INDICATIONS”).
When starting, or stopping treatment with Capsicum spp. and Curcuma longa containing products, including TURMERYNNE® capsules, patients with bleeding disorders should have increased monitoring of their INR (International Normalised Ratio) levels (see “CONTRA-INDICATIONS”).
TURMERYNNE® capsules should be used with care in patients with diabetes as curcumin and Capsicum spp. may decrease blood sugar levels. Diabetic patients should monitor their blood sugar levels when taking TURMERYNNE® capsules (see “CONTRA-INDICATIONS”).
TURMERYNNE® capsules should be used with care in patients with hypertension. Theoretically Capsicum spp. may increase blood pressure.
TURMERYNNE® capsule should be used with caution in patients with iron deficiency. Patient should monitor their iron levels (see “CONTRA-INDICATIONS”).
TURMERYNNE® capsules should be used with care in patients undergoing surgery. Patients should discontinue use at least 2 weeks before elective surgical procedures (see “CONTRA-INDICATIONS”).
TURMERYNNE® capsules should be used with care in patients with hormone-sensitive cancers. Theoretically, turmeric might have mild estrogenic effects. Until more is known, advise women with hormone-sensitive conditions to use turmeric cautiously.
When starting, or stopping treatment with capsicum and turmeric containing products, including TURMERYNNE® capsules, patients taking warfarin (or other coumarin anti-coagulants) should have increased monitoring of their INR (International Normalised Ratio) levels (see “INTERACTIONS”).
TURMERYNNE® capsules should be used with care in patients taking sedative medications, including midazolam, as it may increase its sedative effects (see “INTERACTIONS”).
The use of TURMERYNNE® capsules in children and adolescents under 18 years of age is not recommended due to lack of adequate data (see “DOSAGE AND DIRECTIONS FOR USE”).
Effects on the ability to drive or use machinery: No studies on the effect of TURMERYNNE® capsules on the ability to drive or operate machines have been performed. It is unlikely that TURMERYNNE® capsules will affect the ability to drive or operate machines.INTERACTIONS:
The herbs in TURMERYNNE® capsules may interact with the following medicines:
- Theophylline: Capsicum and piperine may enhance theophylline absorption.
- Beta blockers: curcumin may decrease or increase absorption. Piperine may increase absorption of propranolol.
- Sulfasalazine: Curcuma longa might increase absorption of sulfasalazine.
- Oestrogen: Curcuma longa might decrease the effects of oestrogen
- Lithium: Piper nigrum may increase levels of lithium.
- Rifampin: piperine might increase absorption.
- Norfloxacin: Curcuma longa might increase levels
Advise patients to take any of the above-mentioned medicines at least 2 hours before or after TURMERYNNE® capsules (see “DOSAGE AND DIRECTIONS FOR USE”).
Capsicum spp. and Curcuma longa, as in TURMERYNNE® capsules, may potentially increase the effect of oral anti-coagulants and anti-platelet drugs (e.g. warfarin, aspirin, clopidogrel, dalteparin, enoxaparin, heparin) when taken concomitantly. Patients taking anti-coagulants or anti-platelet medicines should have their INR levels monitored more frequently when taking TURMERYNNE® capsules (see “WARNINGS AND SPECIAL PRECAUTIONS”).
Piper nigrum, as in TURMERYNNE® capsules, may increase the effect of medications for epilepsy when taken concomitantly. Patients taking these medications should use TURMERYNNE® capsules with caution and be monitored closely. Some of these medications include carbamazepine and phenytoin.
Theoretically, Capsicum spp. and Curcuma longa, as in TURMERYNNE® capsules, may enhance the blood glucose lowering effects of anti-diabetic medicines. Patients on anti-diabetic medicines should monitor their glucose levels closely when taking TURMERYNNE® capsules.
Theoretically, Piper nigrum and Curcuma longa might increase levels of p-glycoprotein substrates. Some of these medicines include chemotherapeutic agents, anti-fungals, protease inhibitors, H2 agonists, calcium channel blockers, digoxin, corticosteroids, erythromycin, cisapride, fexofenadine, cyclosporine, loperamide and quinidine.
Curcuma longa, as in TURMERYNNE® capsules, may increase the sedative effects of midazolam. Patients taking midazolam should use TURMERYNNE® capsule with caution (see “WARNINGS AND SPECIAL PRECAUTIONS”).
Piperine increases the bio-availability of curcumin in Turmeric. This may increase the potential of curcumin to interacting with other medicines.
There is some evidence that Curcuma longa and/or curcumin, Capsicum spp. and Piper nigrum may interact with CYP3A4 enzymes and increase bioavailability of medicines metabolised by cytochrome P450 isoenzymes CYP3A4. Patients taking medicines metabolised by these enzymes should use TURMERYNNE® capsules cautiously. These medicines include calcium channel blockers, chemotherapeutic agents, anti-fungals, glucocorticoids, alfentanil, cisapride, fentanyl, lidocaine, losartan, fluoxetine, omeprazole, ondansetron and fexofenadine.
There is some evidence that Curcuma longa may interact with CYP1A2 enzymes and increase the bio-availability of medicines metabolised by cytochrome P450 1A2 isoenzymes CYP1A2. Patients taking medicines metabolised by these enzymes should use TURMERYNNE® capsules cautiously. Some of these medicines include clozapine, fluvoxamine, haloperidol, imipramine, olanzapine, pentazocine, propranolol and zolmitriptan.
There is some evidence that Curcuma longa and Piper nigrum, as in TURMERYNNE® capsules, may increase levels of certain anti-neoplastic agents such as docetaxel, paclitaxel, etoposide, vinblastine and vincristine.
Theoretically, Curcuma longa may decrease the absorption of iron. Patients taking iron should monitor their iron levels when taking TURMERYNNE® capsules.PREGNANCY AND LACTATION:
The safety and efficacy of TURMERYNNE® capsules during pregnancy and lactation have not been established. Capsules should therefore not be taken during pregnancy and lactation.DOSAGE AND DIRECTIONS FOR USE:
The recommended daily dose should not be exceeded. Do not tamper with capsule.
Adults (18 years and older): Take 2 capsules twice daily with meals or as prescribed.
Children (under 18 years of age): Not recommended for use (see “WARNINGS AND SPECIAL PRECAUTIONS”).
Theophylline, beta-blockers, sulfasalazine, oestrogen, lithium, rifampicin and norfloxacin must be taken at least 2 hours before or after TURMERYNNE® capsules (see “INTERACTIONS”).SIDE-EFFECS:
The following side-effects may occur with the use of TURMERYNNE® capsules.
Endocrine disorders: Frequency unknown: Reduced blood glucose, increase plasma insulin.
Psychiatric disorders: Frequency unknown: Addiction.
Nervous system disorders: Frequency unknown: Dizziness, hyperalgesia, vertigo.
Vascular disorders: Frequency unknown: Increased bleeding, myocardial infarct, hypertension and tachycardia.
Gastrointestinal disorders: Frequency unknown: Gastro-intestinal irritation, mouth and throat irritation, stomach discomfort, dyspepsia, diarrhoea, constipation, yellow hard stools, abdominal distention, gastro-oesophageal reflux, nausea, flatulence, ulcer aggravation, vomiting and liver damage.
Skin and subcutaneous disorders: Frequency unknown: Photosensitivity, pruritus, oedema.
Renal and urinary disorders: Frequency unknown: Kidney damage.KNOWN SYMPTOMS OF OVERDOSAGE AND PARTICULARS OF ITS TREATMENTS:
The following symptoms may be experienced in the event of an overdose: Tachycardia, hypertension, hypertensive crisis and myocardial infarct. Contact a poison control centre in area.IDENTIFICATION:
Clear size 0 all vegetable capsule containing dark orange herbal powder.PRESENTATION:
90 Capsules packed in a 125ml amber glass bottle with light gold/mustard screw cap and safety seal insert.STORAGE INSTRUCTIONS:
Store at or below 25 ºC in a dry place. Protect from light. KEEP OUT OF REACH OF CHILDREN.REGISTRATION NUMBER:
To be allocated.NAME AND BUSINESS ADDRESS OF THE HOLDER OF THE CERTIFICATE OF REGISTRATION:
Flora Force Heath Products (Pty) Ltd. Unit 3 Regent Park, Bell Crescent, Westlake, Cape TownDATE OF PUBLICATION:
To be allocated.
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Supports the immune system as well as the digestive system. A must in supportive treatment during tumour and AIDS related therapies. The combination includes herbs that have anti inflammatory, anti-septic and anti-microbial actions, as well as powerful detoxification and regeneration ingredients. The protective action prevents cell damage when exposed to radiation. This formula can be used protectively to strengthen general body health after long periods of stress that make one vulnerable to diseases that result from cellular changes. 10g Ingredients: Arcticum lappa, Rheum palmatum, Rumex ascetosella, Ulmus rubra.
Original ESSIAC formula in capsules. An important overall preventative health protector. Supports the immune system and the digestive system. A must in supportive treatment during tumour- and AIDS-related therapies. The combination includes herbs that have anti-inflammatory, anti-septic and anti-microbial actions, as well as powerful detoxification and regeneration ingredients. The protective action prevents cell damage when exposed to radiation. This formula can be used protectively to strengthen the general body health after long periods of stress that makes one vulnerable to diseases that result from cellular changes. 460mg, 90 capsules Ingredients: Each capsule contains: 215mg Arcticum lappa, 12mg Rheum palmatum, 187mg Rumex ascetosella, 46mg Ulmus rubra.