Flora Force Liver Flush Capsules Package Insert
Scheduling status: C0
Proprietary name (and dosage form): Flora Force Liver Flush Capsules.
Composition: Each capsule contains 78mg Cinnamomum zeylanicum, 78mg Centaurium erythraea, 78mg Rhamnus purshianus, 78mg Zingiber officinalis, Cynara scolymus 78mg
Pharmacological classification: Category D Western Herbal Medicine
Pharmacological action: 11.10 Gastro-Intestinal tract, Others
Indications: Herbal medicine acting on the liver and kidneys, purifying the blood and is an excellent tonic. Aids the digestive function and assists bile production.
Contra-indications: Persons with known allergies to any of the ingredients.
Not indicated for use by children.
Not indicated in pregnancy, stomach or peptic ulcers, inflammatory bowel disease, Crohn’s disease, ulcerative colitis severe abdominal pain and allergic hypersensitivity,
Caution is advised for diabetics to monitor blood sugar levels.
Avoid in gall bladder conditions where increased bile flow might cause obstruction
Not to be taken by children under age 12 or generally debilitated persons due to water and electrolyte loss. Do not use in acute diarrhoea or during menstruation.
Warnings: Do not use continuously longer than 14 days (2 weeks) except under medical supervision. Do not take this medicine if you have gall stones.
Surgery Stop use of Liver flush capsules at least 2 weeks before surgery.
Rhamnus purshianus (cascara) a stimulant laxative herb which can decrease potassium levels.
This has effect on the action of:
Anti-arrhythmic drugs – Digoxin (Lanoxin) interacts with cascara and can potentiate the action of cardiac glycosides.
Anti- inflammatory drugs and Corticosteroids increase potassium deficiency
Diuretics concomitant use of thiazide diuretics increase the potassium deficiency.
chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, HydroDiuril, Microzide), and others.
Decreased effectiveness of oral drugs resulting from insufficient absorption from stimulant effect of cascara in the reduced transit time through bowel.
Dehydration and low mineral levels in body if taken together with other stimulant laxatives. Stimulant laxatives include:
bisacodyl (Correctol, Dulcolax), castor oil (Purge), senna (Senokot), and others.
Warfarin (Coumadin) interacts with cascara Diarrhea can increase the effects of warfarin and increase the risk of bleeding. Cinnamomum zeylanicum can decrease blood sugar in type 2, in diabetics on medication blood sugar level needs to be monitored and adjusted as required.
Drugs include: glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.
Surgery: stop Liver flush capsules 2 weeks prior to surgery to avoid interference with control of blood sugar levels.
Zingiber officinalis (Ginger)
Anti-coagulant, anti-platelet drugs interact with ginger and increase the chances of bruising and bleeding. Drugs: include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin). Phenprocoumon. Warfarin (Coumadin)
Diabetic medication interacts with ginger. Monitor blood sugar levels to prevent hypoglycaemic reaction.
Drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others. Anti-hypertensive drugs – calcium channel blockers interacts with ginger and can give symptoms of irregular beat or hypotension. Drugs include nifedipine (Adalat, Procardia), verapamil (Calan, Isoptin, Verelan), diltiazem (Cardizem), isradipine (DynaCirc), felodipine (Plendil), amlodipine (Norvasc), and others.
Pregnancy and Lactation: Not to be used during pregnancy or lactation.
Dosage and directions for use: Take one to two capsules three times daily, or as prescribed.
Before taking this medicine ensure that condition has been diagnosed by a practitioner. Should condition not improve within 14 days do consult a practitioner.
Side-effects and special precautions: Symptoms of dehydration.
Symptoms of hypoglycaemia.
May cause a mild, transient laxative effect in some individuals.
Contains Rhamnus purshianus: concomitant use of thiazide diuretics may cause increased potassium deficiency.
See warnings: Stop Liver Flush or reduce the dosage.
Known symptoms of over-dosage and particulars of its treatment:
Diarrhoea and lowered blood sugar levels.
Large quantities can cause mucosal irritation, gastritis and vomiting. Severe abdominal pain with griping, nausea and diarrhoea, Habituation and chronic use result in weakness, hypokalaemia and. Children and underweight individuals needs to be treated as serious.
Overdose treatment is symptomatic and supportive with fluids and electrolytes.
Identification: Clear size 0 all vegetable capsule containing greenish brown herbal powder.
Presentation: 60 Capsules packed into 125ml amber glass bottle with dark green screw cap and safety seal insert, 500 capsules packed into 109x117mm securitainer with tamper evident seal.
Storage instructions: Store below 25ºC. KEEP OUT OF REACH OF CHILDREN.
Registration number: To be allocated.
Applicant: Flora Force Health Products (Pty) Ltd., PO Box 426, Rondebosch, 7701, Cape Town
Date of publication: 07/09/2015